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It may not have been dosed correctly." 'Losing 8 litres of fluid a day' on retatrutide Dr Holt, a gastroenterologist who focuses on the digestive system, including the stomach, intestines and liver, treated patients who had "become very unwell" after injecting high doses of retatrutide

The GLP-1 receptor agonist exenatide reduces serum TSH by its effect on body weight in people with type 2 diabetes

It's only approved to treat type 2 diabetes, but people taking it do lose weight

Retatrutide causes a sustained increase in resting heart rate via hormonal pathways, while caffeines effect is typically more acute and transient

PMID: 40617296