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Phase Cag introduction Weeks 9-12 Tirzepatide 5.0 mg/week (hold) Cagrilintide 0.25 mg/week Notes Add cagrilintide at the lowest dose

The body efficiently regulates copper through hepatic metabolism and biliary excretion

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For example: Endogenous GHRH has a half-life of ~515 minutes Native GLP-1 is broken down in under 2 minutes Thats why natural peptides are rarely used directly in therapeutics theyre too unstable