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FDA's concerns include potential immunogenicity for certain administration routes, peptide-related impurities, and the fact that Ipamorelin acetate contains unnatural amino acids that add characterization complexity

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Leggios team concluded that the present finding that semaglutide suppresses alcohol intake in different animal models of alcohol misuse provides compelling support for testing semaglutide in future clinical trials in people with AUD. Reference: Chuong V, Farokhnia M, Khom S, Pince CL, Elvig SK, Vlkolinsky R, Marchette RC, Koob GF, Roberto M, Vendruscolo LF, Leggio L

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