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These observations are consistent with the release and retention data described above, whereby the large fraction of free semaglutide drug observed within these hydrogel-based formulations would be expected to be released rapidly, thereby contributing to elevated C max values at early timepoints

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The PDI was used to quantify the extent of dispersion, distribution of size, and vesicle size uniformity within a sample 31

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The Lancet , 402

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2023;24(9):e13596

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Researchers should avoid stacking compounds with overlapping toxicity profiles or contradictory mechanisms

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