The rate constants from our deglutathionylation assays between 6.4 10 4 and 1.4 10 6 M 1 s 1 are very similar to the rate constants for PfGrx or plant and mammalian glutaredoxins from discontinuous or coupled enzymatic assays with other high and low molecular weight GSSR substrates (Table 1) 9,11,14,19 , thus confirming our assay as an alternative reliable method for the direct analysis of enzyme-catalyzed deglutathionylations
However, more important is the practical evidence from a considerable number of the studies, particularly in gastrointestinal research, that intragastric administration or per os administration in drinking water, is equally effective as injections of the supplement administered to rodents, which has been performed in the majority of studies on BPC 157
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Prodrugs - An efficient way to breach delivery and targeting barriers
Additionally, the healthcare providers we consulted recommend that people with an active or suspected cancer diagnosis speak with their doctor to confirm whether epitalon is appropriate for them