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It was originally speculated that the peptide bound in these receptors and increased the rate of metabolism in fat cells, shifting them from a storage mode to a usage mode
Thats how it became the guinea pig for research, since, like us, its dependent every second of every day on vitamin C from diet
Jelovac N et al
This is because MT2 has broader melanocortin receptivity while PT-141 has targeted central nervous system effects
Bibcode:1980BTER....2..159C
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