We need to see how patients fare over several years, not just several months, to truly understand the risk-benefit profile before we can determine its ultimate place in treatment. Having medications like eloralintide, which work through a different mechanism, may provide a vital alternative and increase our ability to personalize treatment for the individual
These are typically temporary and can be managed with medical guidance
A 2025 head-to-head clinical trial comparing FDA-approved tirzepatide to FDA-approved semaglutide for obesity found that tirzepatide produced greater reductions in body weight over 72 weeks
Arthropod cytosolic GSTs are mainly involved in xenobiotic adaptation
These findings, they said, supported the use of semaglutide, on top of usual care, to reduce the risk of major adverse cardiac events in a broad population of people with established atherosclerotic cardiovascular disease and overweight/obesity