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This glucagon-like peptide-1 (GLP-1) receptor agonist is the active ingredient in Wegovy, Rybelsus, and Ozempicthe last of which has become a household name after countless celebrities spread the word that it helped them lose weight
This is likely due to the more established CKD-specific evidence base available for SGLT2is [10,11,12], and the fact that FLOW evaluated semaglutide in patients receiving prior guideline-directed standard of care, limiting generalisability to GLP-1 RAs more broadly as a first-line therapy [8, 9]
[PMID: 4913247] PubMed record related to this compound for laboratory literature review
People tracking their semaglutide dosing should note GI symptoms at each level to identify their personal threshold
