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Canadian Journal of Cardiology , 41(1), 141-149

When GLP-1 receptor agonists are stored incorrectly, the three-dimensional protein structure may become denatured, reducing or eliminating the medication's ability to bind to GLP-1 receptors and exert its glucose-lowering and weight-management effects

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Simultaneously, strategic CDMO moves are underway: Novo Holdings $16.5 billion acquisition of Catalent (plus an $11 billion transfer of three Catalent plants) was explicitly aimed at ramping Wegovy/Ozempic output ( [10] ) ( [11] )