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Store 5-Amino-1MQ according to recommended laboratory handling procedures and protect it from excessive heat, moisture, and direct sunlight

For the brain, where the same mechanism operates, this results from a rise of intracellular calcium concentration, [Ca 2+ ], triggering pericyte contraction during ischaemia, with subsequent pericyte dysfunction or death maintaining the constriction when the arterial blood supply is restored 9

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Anaerobic glycolysis produces only a fraction of the ATP and generates high amounts of lactic acid as a byproduct

Combining these methodologies allowed detection of specific repair outcomes in each strand of a DSB in a time-resolved manner following NHEJ in living cells