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Citation62,Citation63 After the utilization of glucose by the cells throughout the body, insulin release is reduced accordingly and extra available incretins are degraded by the enzyme DPP-4 as a part of homeostasis

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These findings have led to greater interest in understanding the underlying mechanisms of targeting the GIP receptor

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Acta 1830 , 40734090 (2013)

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For example, chronic butyrate administration reduces food intake and body weight via a neural gutbrain axis 280

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