Kim MK, Baek KH, Song KH, Il Kang M, Park CY, Lee WY, et al
For comorbid metabolic diseases, such as diabetes and obesity, the use of GLP-1RAs generally does not increase cancer risk and may offer certain benefits
65 Does the paradox that either GIPR agonist or antagonist exhibits benefits in combination with GLP-1R agonist correlates with the likely reduction of internalization, following the decrement of -arrestin recruitment or the acceleration of the dissociation rate (K off ) between the ligand and receptor, owing to competition between used agonists and antagonists in endogenous GIP
Had all questions addressed and answered
Bharti R, Sharma R (2022) Effect of heavy metals: an overview