What I noticed, and when Week 1: mostly hydration glow, nothing dramatic
Conversely, pernicious anemia resulting from vitamin B12 deficiency may cause infertility or poor pregnancy outcomes
(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)
Constipation tends to worsen with dose titration and stabilize after several weeks at a maintenance dose
doi: 10.1007/s11892-019-1263-x 23 NogalskaASucajtys-SzulcESwierczynskiJ