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Its primary function is as an anti-oxidant, keeping the cells running smoothly and helping the liver remove foreign chemicals such as drugs and pollutants
Since ROS induce tissue damage, thrombosis and red blood cell dysfunction that contribute to COVID-19 disease severity, administration of free radical scavengers could be beneficial for the most vulnerable patients (Laforge et al., 2020)
Its principal molecular activity is G-actin sequestration via the conserved 'LKKTET' actin-binding motif in the N-terminal region
An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis
Cancer Gene Ther
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