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While research on the connection between lactylation and liver IRI is still in its infancy, the livers unique position as the core organ of lactate metabolism suggests that future advancements will likely reveal more lactate-mediated lactylation sites closely related to liver IRI

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2,3 In addition to these mechanisms, GLP-1 RAs also delay gastric emptying, thereby contributing to enhanced postprandial glucose regulation and increased satiety, ultimately supporting reduced caloric intake and weight management