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Some important strategies for lasting success include: * Regular health checks to watch your weight and BMI * Keeping an eye on what you eat and how active you are to avoid gaining weight back * Changing your glp1 therapy as needed to keep it working right and reduce side effects * Adding healthy habits like exercise and balanced meals to your daily routine
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Other ongoing clinical or observational studies not expected to directly support regulatory submissions are not disclosed
In their separate Phase 2 trials, retatrutide monotherapy showed larger weight loss (~24.2% at 48 weeks, 12 mg) than standalone cagrilintide (~10.8% at 26 weeks, 4.5 mg), and indirect network meta-analyses rank retatrutide highly
Management recommendations published in Postgraduate Medicine by an international group of obesity specialists attribute the nausea to a direct central nervous system effect, mediated by GLP-1 receptors in the area postrema
