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Certain mechanisms of action it has for diabetes are also beneficial to those with obesity, such as its ability to help people feel fuller longer

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Semaglutide carries contraindications for individuals with a history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, or hypersensitivity to semaglutide

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This makes it one of the more frequently documented side effects, though it ranks lower than nausea or gastrointestinal changes in terms of severity and patient dropout rates