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Glucagon-like peptide-1 (GLP-1) is a type of incretin hormone that is secreted by intestinal L-cells in response to a meal
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The bodys digestive system is incredibly efficient at its job, but it cannot tell the difference between an efficacious, protein-based medicine and a piece of food
Morroniside, a GLP-1R agonist, reduced mechanical allodynia and thermal hyperalgesia in a dose-dependent manner in a rat model of neuropathic pain, with peak effects within 1 h and lasting over 4 h [38]
this has contributed to acquiring a better physiological understanding of their metabolism in humans, while also highlighting the challenges and limitations of the current trials
