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Management strategies to achieve this composite endpoint have the potential to both reduce costs and improve quality of life [8,9,10, 14, 16]

On eligibility, I used the clinically warranted threshold of BMI 27 with one weight-related comorbidity as used by clinical trials, and the US, Canadian, and European approved label

Constipation can depend on what your lifestyle looks like

While these typically subside within a few days, you should always notify your doctor just in case, Wirtz says

In people without diabetes, some trials have explored dapagliflozin as a monotherapy or in combination with other weight loss agents have been explored