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In vitro, pycnogenol has antioxidant properties that are more potent than vitamins E and C

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As expected, hepsin / mice displayed heightened oxidative stress after APAP exposure compared to wild-type mice, indicated by a significant decrease in GSH and an increase in nitrotyrosine levels, leading to more severe liver damage and mortality

short-term refrigeration at around 39F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines

Normalization with both reference genes provided similar results and, for data presentation, analysis was performed using DHX8 as reference gene