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Lets not ignore the power dynamics
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Semaglutide (GLP-1) is a synthetic long-acting glucagon-like peptide-1 receptor agonist
Orlistat (Alli, Xenical): Blocks fat absorption in the digestive system
Using either a mast cell stabilizer or a medication to reduce prostaglandin E2 synthesis (e.g., a COX2 inhibitor) stopped the hypersensitivity in the animal model of IBS.[ref] In the Lifehacks section (below), youll find a more comprehensive list of substances that also trigger mast cell degranulation
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