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The above article is a modified version of an article originally written by Paul Soprano, which you can find here

This is the moment to choose alignment over ambition, care over control, and integration over exhaustion

Bioactive Iridium nanoclusters with glutathione depletion ability for enhanced sonodynamic-triggered ferroptosis-like cancer cell death

[6] Release of GST-A1 as an indication of cellular necrosis [edit] Increases in serum and urinary GST-A1 have been found in association with hepatocyte and renal proximal tubular necrosis respectively, and have potential for monitoring injury to these tissues

Together these results suggested that the balancing of oxidative cellular status involves the increase in active GSH efflux to extracellular medium [36]