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The safety profile, optimal dosing strategies, and long-term effects in humans have not been fully established
Mechanistically, this may relate to GHK-Cu's ability to upregulate matrix metalloproteinases (MMP-1, MMP-2), enzymes that can fragment collagen if their activity exceeds the body's ability to rebuild
Research suggested that this lipolysis peptide may potentially facilitate the release of fat from adipose tissue while moderating the accumulation of new fat deposits in laboratory models, without appearing to alter caloric intake or appetite or adversely affect insulin sensitivity in these experimental settings
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