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This effect was shown to be independent of NO and the endothelium [113]
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Given these pathophysiological changes, there has been growing interest in the potential therapeutic effects of GLP-1 RAs on MFI, inflammation, and muscle fiber characteristics [77, 82]
I think what the potential efficacy of GLP-1 agonists for substance-use disorders is telling us, is suggesting is that there may be this kind of final common pathway, this core underlying biology of desire, of wanting things that may transcend food or alcohol or other things and may reflect something fundamental about the way the brain processes these feelings
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