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Tumors have evolved a unique microenvironment, and typically display a more acidic condition, hypoxia, overexpressed reactive oxygen species (ROS), and glutathione (GSH) owing to their rapid proliferation and metabolism (Mura et al., 2013

Our approach integrates thermodynamic stability analysis with partition coefficient optimization, ensuring that the hydrophilic GSH payload remains securely entrapped within the aqueous core until it reaches the viable epidermis

Once anesthetized, the right knee joints of the animals were shaved, sterilized, and subjected to an intra-articular injection of collagenase type II

Athletes or individuals with rigorous fitness routines may benefit from more frequent infusions to support recovery and maintain optimal performance