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It's likely that its effects on GLP-1 are part of a bigger picture involving diet, exercise, and overall lifestyle
[25] In human cells with mutant WRN, NAD+ repletion restored normal mitophagy, improved fat metabolism, decreased mitochondrial oxidative stress, and enhanced mitochondrial quality
Importantly, sensitivity analyses confirmed the robustness of the effects of weight and BMI, even after excluding lower-quality studies, whereas the effects of waist circumference did not remain significant in these analyses
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Ethics declarations Data availability The datasets generated and/or analysed during the current study are available from the corresponding author on reasonable request
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