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In addition to an increased rate of psychosocial effects, SJS/TEN survivors have an estimated reduced life expectancy of about 9 years and an increased risk of ensuing higher healthcare-related costs [136, 137]

Even our analytical period contains 4 years of GLP-1RA usage in pediatric population, it is still crucial for future research to explore the underlying mechanisms contributing to this observed association and to validate findings with larger and more diverse datasets

While some users report enhanced local effects, the evidence for superiority over subcutaneous administration remains unclear, and complications including nerve irritation present greater concern

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