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Further prospective trials are required to define its clinical role

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NAC and selenium supplementation have demonstrated beneficial effects on markers of male fertility (Ahmadi et al., 2016

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Recently, a working group from the International Consortium for Health Outcomes Measurement (ICHOM) made recommendations for a standard set of practical and validated psychosocial measures [179], including the WHO-5 Wellbeing Index (WHO-5) [180], Problem Areas in Diabetes (PAID) scale [181], and Patient Health Questionnaire (PHQ-9) [182]