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Globally launched clinical trials like the European study DISCOVERY showed that antiviral drugs (remdesivir, lopinavir and ritonavir in combination, ritonavir given with or without interferon beta and hydroxychloroquine) are unable to efficiently attack COVID-19 progression (Ader et al., 2022)
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At the end of the experiment, mice were anesthetized with 1% sodium pentobarbital (60 mg/kg) intraperitoneal injection
Bromelain ameliorates D-galactosamine-induced acute liver injury: role of SIRT1/LKB1/AMPK, GSK3/Nrf2 and NF-B p65/TNF-/caspase-8,-9 signalling pathways
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