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Lee et al., In the developing brain, substantially high energy demand increases the need for glucose, oxygen and cerebral blood flow (Hagberg et al., Mitophagy is a crucial process to maintain mitochondrial integrity, where damaged mitochondria can be degraded and the intact components can be recycled to generate new functional mitochondria (Benard and Karbowski, 2010)
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rather, it induces an amino acid starvation response by upregulating the expression of SLC38A1, suggesting that SLC38A1 is a major importer of glutamine into these cells 90
Equal concentrations of total RNA (10 g) were size-separated on 1.2% agarose-2.2 M formaldehyde gels and blotted onto Hybond N+ membranes (Amersham Biosciences)