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Your injection volumes are larger
Dehydration reduces circulating volume and can trigger dizziness that feels faint and unstable rather than spinning
If you have or have had depression, suicidal thoughts, or other mental health issues
It is recommended to work closely with a health care provider to adjust dosages accordingly for the patients safety, if needed
A 2025 meta-analysis published in Endocrinology, Diabetes & Metabolism, pooling data from four studies with nearly 29,000 patients, confirmed a consistent advantage for tirzepatide, with an average additional weight reduction of 4.84 kg compared to semaglutide
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