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BRIN-BD11 cells were used throughout this study for their well characterised responses to multiple stimuli, cell culture based convenience and their established intact response to GLP-1R activation both in terms of cAMP and resulting stimulated insulin secretion 36, 37
In addition, antioxidants that protect the liver from ROS damage and lipid peroxidation may be depleted: GSH, vitamin E, vitamin C and beta-carotene were found to be reduced in the NASH setting (38, 39)
Additionally, Medicaid coverage of GLP-1 medications for obesity varies across states, leaving many patients ineligible for coverage depending on where they live
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