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MECHANISMS OF ACTION OF GLP-1 RAs AND MULTI-AGONIST THERAPIES Incretin-based therapies leverage the physiological roles of gut-derived peptide hormones, principally glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptor (GCG) to address the multifaceted pathophysiology of MASLD