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It receives input from the suprachiasmatic nucleus (SCN) of the hypothalamus, which acts as the body master clock, and translates that input into hormonal signals that synchronize virtually every biological process in your body

Nature 539, 179

But half is not possible

DOI: 10.1186/s13073-026-01630-0 The study received funding from Wellcome, Medical Research Council, European Union Horizon 2020 Programme, the National Institutes of Health (grants U01-DK105535, U01-DK085545 and UM-1DK126185), the National Institute for Health Research Oxford Biomedical Research Centre, the Canadian Institutes of Health Research, the Novo Nordisk Foundation, Boehringer Ingelheim and Diabetes Australia