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One of those earlier human studies may have been too short in duration to show effects, argue the researchers of the new glutathione study published in the May issue of the The aforementioned seven-subject study showed no significant effects on plasma glutathione levels during a 4.5-hour period, but the EJN study authors wrote that the rapid turnover of [glutathione] in human plasma would likely make it difficult to detect an increase in plasma after a single oral dose. It is well known in the science community that glutathione is one of the primary protective molecules in the body

Glutathione: Physiological and clinical relevance

Anti-Doping Agency for participant registration records

There are no other officially reported contraindications specific to NAD+ as of now, but the absence of documented contraindications largely reflects limited clinical study

All animal studies were approved by the Augusta University Institutional Animal Care and Use Committee (#2019-1010)