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Think of glutathione as your bodys superhero antioxidantits made of three parts (cysteine, glycine, and glutamine) and works like your bodys cleanup crew and shield against damage

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Since the activation of lactate-dependent ATP pathway causes lowering of pH, the Na+/H+ antiporter membrane protein pumps protons out of the cells in an attempt to correct the intracellular pH ( All these processes contribute to increase intracellular Ca 2+ levels that consequently enhance the activation of calcium dependent proteases such as calpains that exert their detrimental function during the reperfusion phase when pH was normalized ( The increased intracellular levels of Na and Ca 2+ trigger mitochondria to internalize Ca +2 in their matrix

doi: 10.1021/mp700113r 161 Sharifi-RadJRayessYERizkAASadakaCZgheibRZamWet al

We also found an association with CAD in men but not women