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Alteration of mitochondrial DNA homeostasis in drug-induced liver injury

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In the current study, the decreased serum values of IL-6 in the glutathione group showed similar results to the metformin group, while the results of both groups were significantly better compared with the PCOS group

Limited Antioxidant Effects : Other studies have indicated that while coffee consumption may have some antioxidant effects, the specific benefits attributed to coffee enemas remain unproven

203 Therefore, reviews or intervention strategies discussing SIRT1 in MASLD must avoid the oversimplified assumption that SIRT1 activation is always beneficial and instead adopt a refined, stage- and cell-specific framework