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However, contrary to expectations, the deletion of the Nfe2l2 gene had a moderate impact on the course of the disease in SOD1 G93A mice and negatively affected only a few Nrf2-regulated antioxidant enzymes, thus suggesting that several Nrf2-target genes can also be regulated independently of Nrf2 in ALS mice [270, 271]
Well-known as the "master antioxidant," it performs vital functions like detoxifying the body, cell rejuvenation, boosting the immune system, the body's defense against oxidative stress, and its role in skin whitening
Molecular Aspects of Medicine, 30(1-2), 112
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The ratio of GSH to GSSG is often used to gauge the level of oxidative stress in cells, with higher concentrations of GSSG implying more oxidative stress Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use
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