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26, 27 Furthermore, it is known that GPxs are involved in the regulation of platelet activity, endothelial function, platelet-dependent thrombosis and propensity for vascular thrombosis, and a deficiency of this enzyme has been associated with platelet-dependent thrombosis and arterial ischemic stroke

Treatment did not adversely affect kidney weight or overall organ architecture, indicating selective targeting without compromising healthy renal tissue

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