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Apart from its glucose-lowering effects, metformin has shown significant progress in the treatment of cancer, cardiovascular diseases, and kidney disorders [47,48,49,50]
Moreover, GPx3 may be significant during the preimplantation period of pregnancy in O/PEs and female genital organs, where it could protect cells from oxidative stress during the hormone and protein synthesis, and during the cell metabolism
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However, glutathione is generally considered safe for most individuals when taken within recommended dosages
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