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One of the main causes of MDR is the overexpression of transporters on the membrane of cancer cells that actively export the anti-cancer drugs out of the tumor cells, thereby increasing their survival rates (Leslie et al., 2001
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The reactive oxygen species (ROS) is able to induce the proliferation of leiomyoma smooth muscle cells and it is also necessary for triggering the MAPK1/MAPK3 signaling pathway, which contributes to leiomyoma smooth muscle cell proliferation (Mesquita et al., 2010)
Nucleated red blood cells contribute to the host immune response against pathogens
