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(Berl.) 199, 615624

The 12 mg dose in TRIUMPH-4 led to a 28.7% loss over 68 weeks, while tirzepatide in the SURMOUNT-1 trial produced approximately 22.5% loss over 72 weeks

results showed HbA1c reductions up to 2.02 percentage points with 12 mg [3], modestly exceeding the semaglutide result, though again the trials are not directly comparable