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The study suggests that RYGB surgery showed a much larger and longer-lasting effect compared to diet restrictions, and medications like tirzepatide and semaglutide also demonstrated a prolonged period of effective weight loss

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And the same goes for this type of statement

A: Hexarelin produces a larger GH response but activates a broader hormonal profile (including ACTH and prolactin in some studies) and shows greater receptor desensitization