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Scientists believe corticosteroids can cause depression and mood symptoms by lowering levels of serotonin, a chemical in the brain that is involved in mood regulation

A 42-year-old female with longstanding profound fatigue, chronic pain, asthma, multiple food intolerances, GI symptoms including diarrhea, urticaria, food cravings, weight gain, and migraine who was essentially housebound due to constant exhaustion (she estimated 30% of normal energy) took tirzepitide at 3.75 mg principally to address obesity

J Dermatol Case Rep (2014) 8(3):606

Once you are stable on your dose (typically 4-8 weeks into titration),you may transition back to free-weight compound movements as tolerated

If you miss a dose, make an appointment as soon as possible, as long as its within seven days of the missed injection