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Note that a 200 mg dose is 1.0 mL a relatively large subcutaneous volume

A current drawback of intracellular roGFP2-based mechanistic studies is, however, that the mechanisms and structure-function relationships still have to be validated in vitro

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For example, a fact that the formation of protein corona on anti-HER2 antibody-functionalized lipid nanocarriers led to a significant reduction in cellular uptake by HER2 +ve breast cancer cells, which resulted in compromised targeting capability, has been established by the study conducted by Marchal et al

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