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K., Liu, B., Cui, X., Brown, K., & SURPASS-2 Investigators
Whole food carbohydrate sources like legumes, sweet potatoes, and whole fruit can be reintroduced gradually while monitoring weight and metabolic markers
Transcriptomic analysis in this research downregulated mitochondrial oxidative phosphorylation pathways and reduced expression of proteins involved in hepatic lipid uptake, without significantly altering other major liver metabolic pathways findings that continue to inform research into incretin receptor agonism and hepatic lipid metabolism
Retatrutide Phase 2 data in diabetic participants showed HbA1c reductions up to 2.4% from baseline