In vivo studies have shown that microneedle-mediated delivery of semaglutide analogs leads to comparable or improved pharmacokinetics versus subcutaneous injections, with potential for once-weekly or biweekly dosing schedules [42]
Other medications that you may take using subcutaneous injection: Blood thinners Eczema medications Fertility drugs Epinephrine Pain medication Growth hormone Octreotide Mecasermin (insulin-like growth factor) Glucagon Subcutaneous Injection Sites There are certain areas of your body where you should use the needle during a subcutaneous injection: Stomach (except for one inch around your belly button), below your ribs, and above your hip bones
Ogunremi et al believe that the lack of data is related to the very recent popularity of GLP-1 agonists for weight loss and no studies specifically assessing dermatologic adverse effects have been conducted
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Timothy Garvey, MD, of the University of Alabama at Birmingham, reviews the latest data on CagriSema and emerging amylin-based therapies presented at the 2026 ADA Scientific Sessions