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In 4-week clinical studies, the average ADHD-RS score was reduced by: 18.3 to 26.7 in children ages 6 to 17 who took Vyvanse, depending on their dose 16.2 to 18.6 in adults who took Vyvanse, depending on their dose 6.2 to 12.8 in children ages 6 to 17 who took a placebo 8.2 in adults who took a placebo Vyvanse was also effective in longer studies in adults and children

doi: 10.3390/ijms23042144 6 LiuYGuRGaoMWeiYShiYWangXet al

Cooled the compound to 5-10C and acidified by using IN HC1 solution and stirred for 15 min at same temperature

Yes, for most patients

Suppose it was 70-30 or 50-50, perhaps I would have also been inclined to look at other options