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Rekha Kumar, MS, MD, endocrinologist, obesity medicine specialist and senior medical advisor at Found, describes Eli Lillys retatrutide (nicknamed reta) as a next-generation weight-loss medication that is still awaiting FDA approval, but currently in late-stage clinical trials

After being stimulated by fibrogenic factors, HSCs change from vitamin A-storing latent cells to active cells that resemble myofibroblasts, depositing an abundance of ECM, especially type I collagen

Most observe their cardiometabolic markerssuch as blood sugar, cholesterol, and blood pressurenormalize within 1.4 years

GLP-1 agonist liraglutide improves ouabain-induced mania and depressive state via GSK-3beta pathway