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Over time, as the HPA axis becomes dysregulated and the bodys stress-response resources are depleted, cortisol levels may begin to flatten or drop, particularly in the morning when they should be at their highest

They can do that

Doses are adjusted based on lab results, how the patient responds, and individual assessments

A synapse, defined as a narrow point of contact characterized by asymmetric junctions known as the presynaptic and postsynaptic compartments, is evident through electron microscopy by distinct electron density on either side of the junction 68,74